what is tea tree oil

Satchell AC, Saurajen A, Bell C, Barnetson RS. Treatment of dandruff with 5% tea tree oil shampoo. J Am Acad Dermatol 2002; 47:852-855.

PRACTICE MENDATIONS Daily shampooing with 5% tea tree oil reduces the severity and extent of dandruff. Overall improvement is similar to topical treatment with ketoconazole or terbinafine.

1,2 Tea tree oil is a good alternative for patients who prefer a natural product, dont mind daily hair washing, and can tolerate the distinctive tea tree oil fragrance. BACKGROUND Since dandruff control requires long-term management, treatment choice will depend on ease and frequency of administration, costs, and side effect profiles of the therapeutic agents.

Tea tree oil, a natural product, has antifungal activity against Pityrosporum ovale, which is thought to be the causative agent of dandruff. POPULATION STUDIED A total of 126 patients with chronic dandruff, 14 years of age or older, were recruited by advertising in Australia.

Baseline severity was assessed by whole-scalp lesion scores. Exclusion criteria were very mild or very severe dandruff, significant change in severity during a 2-week washout period, or itant impacting clinical conditions.

STUDY DESIGN AND VALIDITY Patients were randomized and matched for sex, race, dandruff severity, severity of symptoms, and medical history. The authors could not be contacted for specific information on randomization or allocation concealment.

Since tea tree oil has a distinctive odor, patients were asked not to apply the test product the day of assessment to maintain blinding by those assessing es. Subjects self-reported scaliness, itchiness, and greasiness.

Only 1 patient was lost to follow-up after 4 weeks. Recruiting through advertising may have influenced the type of patient and dandruff studied.

The 4-week study period did not assure the absence of long-term problems. Since subjects could detect the smell of the active ingredient and were thus not blinded, self-assessments of scaliness, itchiness, and greasiness were prone to reporting bias.

The severity scale criteria seem subjective, and there was no mention of intra- or interexaminer reliability. Analysis was intention-to-treat.

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